Recent studies show that peak systolic velocity of middle cerebral artery (MCA-PSV) is an accurate non-invasive method for evaluating fetal anemia. This method is expected to provide additional information to, or even substitute the invasive method, such as amniocentesis or cordocentesis.
We experienced a case of severe fetal hemolytic anemia due to rhesus alloimmunization, which needed 6 times of repeated fetal transfusions. We measured the pre- and post-transfusion MCA-PSV values. Pre-transfusion MCA-PSV values were near the 1.5 MoM line, but post-transfusion values were near the median line on the Mari's reference curve chart. The baby was born at 35 weeks 5 days of gestation, and received two partial exchange transfusions. He is well thereafter.
We experienced a case of repeated fetal transfusions, in which MCA Doppler appears to be a good adjunct assessment of fetal anemia, and we report this case with a brief review of the literature.